Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics, COA of Formula: https://www.ambeed.com/products/5813-64-9.html, 5813-64-9, Name is 2,2-Dimethylpropan-1-amine, SMILES is CC(C)(C)CN, belongs to amides-buliding-blocks compound. In a document, author is Lu, Yu-Ke, introduce the new discover.
A chemoselective C-N coupling (Buchwald-Hartwig-type) reaction of diarylamines with aryl halides bearing non-protected amino or hydroxy groups proceeds in the presence of a simple iron catalyst. Upon treatment with Grignard reagents, various diarylamines can be cross-coupled with halocarbazoles, haloindoles, haloanilines, and halophenols to afford the corresponding triarylamines, without the undesired dimerization or oligomerization of the starting aryl halides. DFT studies on the dimeric iron amide intermediates reveal that the reductive elimination can be the selectivity determining step. Finally, a short-step synthesis of a thermally activated delayed-fluorescence emitter, DACT-II, demonstrates the synthetic utility of the present method.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 5813-64-9. COA of Formula: https://www.ambeed.com/products/5813-64-9.html.
Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics