Reactions catalyzed within inorganic and organic materials and at electrochemical interfaces commonly occur at high coverage and in condensed media, causing turnover rates to depend strongly on interfacial structure and composition, 62009-47-6, Name is 2-Aminomalonamide, SMILES is O=C(C(C(N)=O)N)N, in an article , author is Su, Shao-Hua, once mentioned of 62009-47-6, Application In Synthesis of 2-Aminomalonamide.
To explore the biological properties of rosin derivatives, two dehydroabietic acid derivatives N-(5-dehydroabietyl-1,3,4-thiadiazole)-yl-pyridine-2-carboxamide (DTPC) and di-N-(5-dehydroabietyl-1,3,4-thiadiazole)-yl-pyridine-2,6-carboxamide (DDTPC) with 1,3,4-thiadiazole, pyridine and amide moieties were designed and synthesized according to superposition principle of activity group. They interact with calf thymus DNA (CT DNA) via intercalation based on the results of circular dichroism (CD) and fluorescence spectroscopy, DNA denaturation and viscosity studies. Fluorescence and CD spectral experiments indicate that they might be transported and stored by protein like bovine serum albumin (BSA). MTT assay was further carried out to examine their cytotoxicity, they both showed selective cytotoxicity and DTPC exhibited better cytotoxicity. The anti proliferative effect of DTPC toward A431 cell line was stronger than that of clinically used cisplatin and oxaliplatin. In addition, the cytotoxicity of DTPC and DDTPC was closely related with their DNA binding ability. (c) 2020 Published by Elsevier B.V.
But sometimes, even after several years of basic chemistry education, it is not easy to form a clear picture on how they govern reactivity! 62009-47-6, you can contact me at any time and look forward to more communication. Application In Synthesis of 2-Aminomalonamide.
Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics