Chemistry, like all the natural sciences, Computed Properties of https://www.ambeed.com/products/98-10-2.html, begins with the direct observation of nature— in this case, of matter.98-10-2, Name is Benzenesulfonamide, SMILES is O=S(C1=CC=CC=C1)(N)=O, belongs to amides-buliding-blocks compound. In a document, author is Miyahara, Masayoshi, introduce the new discover.
Sinapic acid (SNP) is a nutraceutical compound of hydroxybenzoic acid derivative which possesses antioxidant, anti-microbial, anti-inflammatory, anti-cancer, and anti-anxiety activity properties. In the present work, two cocrystals of SNP with two active drug ingredients such as Ethenzamide (ETZ) and 2-chloro-4-nitrobenzoic acid (CNB) are reported. Both the cocrystals were synthesized via simple solvent evaporation method and the crystal structures were characterized by Single Crystal X-ray Diffraction (SC-XRD) techniques. The cocrystals were formed via robust acid-amide heterosynthon and acid acid homosynthon between SNP and drug molecules. Both the cocrystals were crystallized in monoclinic crystal system with P 2(1)/c space group. The synthesized cocrystals were further characterized by DSC, PXRD, FT-IR, and H-1 NMR techniques. The solubility study in purified distilled water and in 0.1 N HCI solution demonstrate that there was no increment in the solubility of drug molecules in the cocrystals in both purified water and in 0.1 N HCl solution. The synthesized cocrystal exhibited six months stability at ambient conditions (similar to 25 degrees C, 60-65% RH). (C) 2018 Elsevier B.V. All rights reserved.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 98-10-2. Computed Properties of https://www.ambeed.com/products/98-10-2.html.
Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics