Chemistry is traditionally divided into organic and inorganic chemistry. The former is the study of compounds containing at least one carbon-hydrogen bonds. 56-45-1, Name is H-Ser-OH, molecular formula is C3H7NO3, belongs to amides-buliding-blocks compound, is a common compound. In a patnet, author is Bergkemper, Melanie, once mentioned the new application about 56-45-1, Category: amides-buliding-blocks.
A series of peptide dendrimers and their conjugates with antimicrobial agent FMDP (N-3-(4-methoxyfumaroyl)-(S)-2,3-diamino-propanoic acid) were synthesized. The obtained compounds were tested for the antibacterial and antifungal activity. All novel dendrimers displayed much better activity against the tested strains than FMDP itself. Moreover, their conjugates with FMDP also exhibited antimicrobial activity. The most promising molecules were tested against a broad selection of fungal strains. The analysis of their antifungal properties indicates that the examined molecules are efficient growth inhibitors of fluconazole-resistant hospital-acquired strains. Moreover, an application of amphiphilic branched peptides such as FMDP carriers suggests that transport mechanism involves more likely the cell membrane perturbation than the mediation of the specific transport proteins. The activity of obtained compounds strongly depends on the specific structure of the molecule.
We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 56-45-1. The above is the message from the blog manager. Category: amides-buliding-blocks.
Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics