Application of 1492-24-6, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 1492-24-6, Name is H-Abu-OH, SMILES is CC[C@H](N)C(O)=O, belongs to amides-buliding-blocks compound. In a article, author is Grabrijan, Katarina, introduce new discover of the category.
BF3 center dot OEt2-Catalyzed Vinyl Azide Addition to in Situ Generated N-Acyl Iminium Salts: Synthesis of 3-Oxoisoindoline-1-acetamides
BF3 center dot OEt2-catalyzed nucleophilic addition of vinyl azides to in situ generated N-acyl iminium salts obtained from 3-hydroxyisoindolinones is described in this article. The procedure is operationally simple, mild, additive, and metal-free. The reaction proceeds smoothly at ambient temperature with a wide range of 3-hydroxyisoindol-1-ones and vinyl azides to afford 3-oxoisoindoline-1-acetamides (32 examples) in high yields (up to 97%). Furthermore, the synthetic utility of this methodology is depicted by exploiting the reactivity of an amide functionality in the products.
Application of 1492-24-6, Consequently, the presence of a catalyst will permit a system to reach equilibrium more quickly, but it has no effect on the position of the equilibrium as reflected in the value of its equilibrium constant.I hope my blog about 1492-24-6 is helpful to your research.