Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 13433-00-6, Name is Diethyl 2-aminomalonate hydrochloride, SMILES is O=C(OCC)C(N)C(OCC)=O.[H]Cl, belongs to amides-buliding-blocks compound. In a document, author is Li, Jianpeng, introduce the new discover, Application In Synthesis of Diethyl 2-aminomalonate hydrochloride.
Aerobic Oxidation for the Synthesis of N-Substituted alpha-Hydroxyl Phenylacetamides Promoted by Base
alpha-Hydroxyl amides are important skeleton and valuable intermediates that present in many natural products, pharmaceutical active compounds, and organic functional materials. The main methods for synthesis of alpha-hydroxyl amides are either through amidation of alpha-hydroxyl acids, or by reduction of alpha-keto amides. Herein, a convenient potassium hydroxide/dimethyl sulfoxide promoted aerobic oxidation reaction to prepare N-substituted alpha-hydroxyl phenylacetamides is reported in good to high yields. 21 corresponding products were obtained and characterized by H-1 NMR, C-13 NMR and HRMS. The molecular structure of 2-(2-bromophenyl)-2-hydroxy-N-(p-tolyl) acetamide (2a) was confirmed by using single-crystal X-ray analyses.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 13433-00-6 is helpful to your research. Application In Synthesis of Diethyl 2-aminomalonate hydrochloride.