Application of 1492-24-6, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 1492-24-6, Name is H-Abu-OH, SMILES is CC[C@H](N)C(O)=O, belongs to amides-buliding-blocks compound. In a article, author is Henen, Morkos A., introduce new discover of the category.
Reactions of 2-Aminobenzohydrazide and 4-Oxo Pimelic Acid Catalyzed by Iodine in Ionic Liquids
The reactions between 2-aminobenzohydrazide and 4-oxopimelic acid catalyzed by iodine using ionic liquids as green solvents were studied. The results showed that when there was no substituents on N atoms attached to amide group of the hydrazide, it will successfully constructed three new rings and formed pyridazinoq[6,1-b] pyrroloq[1,2-a] quinazoline-1,6,9(7H)trione derivatives. The structure of 2,3,4,5-tetrahydro-1H, 9H-pyridazinoq[6,1-b] pyrroloq[1,2-a] quinazoline-1,6,9(7H)-trione (3a) was confirmed by X-ray diffraction analysis. However, when the substituents were aryl groups, the pyridazine ring did not closed as expected due to the steric hindrance, and gave tetrahydropyrroloq[1,2-a] quinazolin-3a(1H))-propionic acid derivatives. The advantages of this approach were the simplicity of the synthesis route, environmental protection, easy operation and high efficiency.
Application of 1492-24-6, The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 1492-24-6 is helpful to your research.