Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. , Category: amides-buliding-blocks, 27532-96-3, Name is H-Gly-OtBu.HCl, molecular formula is C6H14ClNO2, belongs to amides-buliding-blocks compound. In a document, author is Chavan, Kamlesh H., introduce the new discover.
Imidazolium chloride-catalyzed synthesis of benzimidazoles and 2-substituted benzimidazoles from o-phenylenediamines and DMF derivatives
A facile, general, and economical synthesis of diversely functionalized benzimidazoles and 2-substituted benzimidazoles has been realized via the imidazolium chloride-catalyzed cyclization of o-phenylenediamines with DMF derivatives. This protocol shows a broad substrate scope for aliphatic, aromatic, and heteroaromatic amides. A series of benzimidazoles and 2-substituted benzimidazoles have been obtained in moderate to excellent yields. (C) 2018 Elsevier Ltd. All rights reserved.
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