One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, such as the rate of change in the concentration of reactants or products with time. 32677-01-3, Name is H-Glu(OtBu)-OtBu.HCl, formurla is C13H26ClNO4. In a document, author is Hwang, Jinkwang, introducing its new discovery. Name: H-Glu(OtBu)-OtBu.HCl.
Synthesis and antimicrobial evaluation of piperic acid amides and their lower homologues
Seven piperic acid amides along with their lower homologs (12) were synthesized using HATU-DIPEA coupling reagent. All the synthesized derivatives were evaluated for their antibacterial activities against Staphylococcus aureus, Pseudomonas aeruginosa, and vancomycin-resistant P. aeruginosa. They were found to be more active on P. aeruginosa than on S. aureus. However, they did not exhibit potent activity on Vancomycin resistant P. aeruginosa. Among the tested compounds, methylenedioxycinnamic acid amide of anthranilic acid (MDCA-AA, 2a) was found to be most active against S. aureus with MIC of 3.125 mu g/ml. The PAS and INH amides of piperic acid were screened against Mycobacterium tuberculosis H37R(a) strain. They were found to be most active among all the tested compounds but were found to be less active than the standard drug, isoniazid.
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