Application of 51-35-4, Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. 51-35-4, Name is H-Hyp-OH, SMILES is O=C(O)[C@H]1NC[C@H](O)C1, belongs to amides-buliding-blocks compound. In a article, author is Niavarani, Zahra, introduce new discover of the category.
Synthesis and antimicrobial activities of novel sorbic and benzoic acid amide derivatives
A series of sorbic and benzoic acid amide derivatives were synthesized by conjugating sorbic acid (SAAD, a(l)-a(7)) or benzoic acid (BAAD b(1)-b(6)) with amino acid esters and their antimicrobial activities were investigated against Escherichia coll., Bacillus subtilis and Staphylococcus aureus, mixed bacteria from rancid milk, Saccharomyces cerevisiae, and Aspergillus niger. The antimicrobial activity of sorbic acid amides was better than that of benzoic acid amides. The minimum inhibitory concentrations (MIC) of compound isopropyl N-[1-oxo-2, 4-hexadien-1-yl]-L-phenylalaninate (a(7)) were 0.17 mM against B. subtilis, and 0.50 mM against S. aureus, while the MIC values of sorbic acid were more than 2 mM respectively. Also, compound a(7) displayed pH-independent antimicrobial activity in the range of pH 5.0-9.0 and was effective at pH 9.0. These results demonstrated that the conjugation of sorbic acid with amino acid esters led to significant improvement of in vitro antimicrobial attributes, but little effect was observed for benzoic acid amide derivatives.
Application of 51-35-4, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. I hope my blog about 51-35-4 is helpful to your research.