Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics, 13404-22-3, Name is H-Ala-OtBu.HCl, SMILES is C[C@H](N)C(OC(C)(C)C)=O.[H]Cl, belongs to amides-buliding-blocks compound. In a document, author is Sasaki, Yoshikazu, introduce the new discover, Quality Control of H-Ala-OtBu.HCl.
Catalytic Cyanation Using CO2 and NH3
Selective cyanation of aryl halides was achieved with CO2 and NH3 as the only sources of carbon and nitrogen, respectively. In the presence of Cu catalysts under low pressure (3 atm), a variety of aromatic iodides and bromides were transformed to the desired nitrile products without the use of toxic metal cyanides. Notably, olefins, esters, amides, alcohols, and amino groups were tolerated. Mechanistic studies suggest that Cu(III)-aryl insertion by isocyanate intermediates is involved. [C-13,N-15]-labeled nitriles were conveniently accessible from the respective isotope-labeled CO2 and NH3 via this methodology.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 13404-22-3 is helpful to your research. Quality Control of H-Ala-OtBu.HCl.