144978-35-8, Name is 1-Boc-D-Pyroglutamic acid ethyl ester, molecular formula is C12H19NO5, belongs to amides-buliding-blocks compound, is a common compound. In a patnet, author is Kaur, Navneet, once mentioned the new application about 144978-35-8, Computed Properties of C12H19NO5.
The Ritter Reaction of 2-Oxoaldehydes at Room Temperature: Divergent Behaviour towards Acid Strength
An efficient, novel, atom economical and selective amidation method for the generation of mono and di-Ritter products using 2-oxoaldehydes under acidic environment at room temperature was successfully developed. The di-Ritter products obtained are accessed in good yields when stirred in the presence of 20 mol % H2SO4, and the mono products were selectively obtained in moderate yields with CuOTf as catalyst. However, the yields of the latter were optimized by the addition of SeO2.
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