Electric Literature of 20859-02-3, As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 20859-02-3, Name is H-Tle-OH, SMILES is CC(C)(C)[C@H](N)C(O)=O, belongs to amides-buliding-blocks compound. In a article, author is Barde, E., introduce new discover of the category.
Synthetic studies toward bicyclic endoperoxides presenting polar side chains
We developed a synthetic strategy for the preparation of tetrahydrofuro[2,3-c][1,2]dioxane and 2,3,8-trioxa[3,3,1]nonanes bearing polar functional groups at C3 and C4, respectively. The synthetic strategy has been applied to the synthesis of 2,3,8-trioxa[3,3,1]nonanes bearing various amides and amines at C3 useful for structure-activity relationships investigation as antiplasmodial compounds. The synthesis of 1 and the reaction conditions identified for its conversion to amides and amines could pose the basis for the use of this class of endoperoxides also in conjugation with other drugs for polypharmacology approaches. (C) 2018 Elsevier Ltd. All rights reserved.
Electric Literature of 20859-02-3, The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 20859-02-3 is helpful to your research.