Synthetic Route of 20859-02-3, Redox catalysis has been broadly utilized in electrochemical synthesis due to its kinetic advantages over direct electrolysis. The appropriate choice of redox mediator can avoid electrode passivation and overpotential. 20859-02-3, Name is H-Tle-OH, SMILES is CC(C)(C)[C@H](N)C(O)=O, belongs to amides-buliding-blocks compound. In a article, author is Bache, Matthias, introduce new discover of the category.
Enantiomeric resolution of ephedrine racemic mixture using molecularly imprinted carboxylic acid functionalized resin
In the current work, we prepared an enantio-selective imprinted resin adsorbent ((+)-EMIP) with remarkable affinity for (+)-ephedrine ((+)-Eph) enantiomer. The phenolic amide derived from 4-hydroxybenzoic acid (HBA) and (+)-Eph ((+)-Eph-HBA) was first synthesized via N,N’-diisopropylcarbodiimide (DIC) activation and then copolymerized with resorcinol and formalin. The template (+)-Eph was then expelled from the resin by alkaline degradation of the amide linkage and the finally obtained (+)-EMIP resin particles exhibited a considerable selectivity toward the (+)-Eph with a capacity reached 220 +/- 1 mg/g. Also, the selectivity studies indicated a higher affinity toward the imprinted (+)-Eph enantiomer as a result of the formation of configuration-matching receptor sites that were able to fit the targeted enantiomer better than its mirror-image. Moreover, the prepared resin was successfully employed in the chiral resolution of (+/-)-Eph racemate using batch technique with (+)-Eph 87.1% enantiomeric excess in the loading supernatant solution and (-)-Eph 44.6% excess in the recovery eluant solution.
Synthetic Route of 20859-02-3, Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. The slowest step in a reaction mechanism is the rate-determining step.you can also check out more blogs about 20859-02-3.