Related Products of 24167-52-0,Some common heterocyclic compound, 24167-52-0, name is 3-Chloro-N,N-dimethylbenzamide, molecular formula is C9H10ClNO, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
N’-cyanobenzimidamide (16.8 g, 115 mmol), Compound 2-4-2 (21 g, 115 mmol) and phosphorus oxychloride (12 mL, 128 mmol) were added to 500 mL of acetonitrile and then stirred under reflux for 1 hour. After cooling to room temperature, the resulting solid was filtered, washed with water and ethanol, and then dried to produce Compound 2-4-3 (27.6 g, yield: 80%).
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 3-Chloro-N,N-dimethylbenzamide, its application will become more common.
Reference:
Patent; LG CHEM, LTD.; KANG, Min Young; PARK, Tae Yoon; CHO, Seongmi; MUN, Jeong Wook; JUNG, Min Woo; LEE, Jung Ha; (29 pag.)US2020/39971; (2020); A1;,
Amide – Wikipedia,
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