Reference of 35303-76-5, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 35303-76-5 as follows.
4-(2-aminoethyl)benzenesulfonamide (0.86 mmol) was added to a THF solution (20 ml) of 1- (3-isocyanatopropyl) -4-methoxybenzene Gt; min. & Lt; / RTI & gt; The reaction mixture was stirred at 40-45¡ã C for 24 hours. The next day, TLC was used to confirm the termination of the reaction. The solvent was distilled off and ammonium chloride (100 ml), 1N HCl solution (50 ml) and ethyl acetate (100 ml) were added to the remaining residue. The organic layer was washed with brine and dried over sodium sulfate. The solvent was distilled off and the residue was adsorbed onto silica gel using methylene chloride. The title compound was then separated and purified by column chromatography using ethyl acetate and hexane
According to the analysis of related databases, 35303-76-5, the application of this compound in the production field has become more and more popular.
Reference:
Patent; CHUNGNAM NATIONAL UNIVERSITY INDUSTRY & ACADEMIC COOPERATION (IAC); JUNG, SANG HUN; WOO, SUN HEE; KIM, SANG KYUM; JEON, EUN SEOK; LEE, YOU JUNG; MANICKAM, MANOJ; JALANI HITESHKUMAR, HITESHKUMAR; SHARMA, NITI; (234 pag.)KR2015/111825; (2015); A;,
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