Application of 3144-09-0, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 3144-09-0, name is Methylsulfonamide belongs to amides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
Embodiment 80Under 80 C , the methanesulfonamide (0.75mmol, 71.3 mg) and (E) – 1,3-diphenyl-2-propen-1-ol (0.5mmol, 105.0 mg) and [BsTdmim]OTf (10mol %, 27.5 mg), 1,4-dioxane 2.0 ml is placed in a dry reaction flask, magnetic stirring reaction for 2h. After the completion of the reaction separation was done using column chromatography (by silica gel column, eluent: petroleum ether/ethyl acetate = 5/1), to obtain white solid (E)-N-(1,3-diphenylallyl)methanesulfonamide 142.1 mg, yield is 99%
The synthetic route of Methylsulfonamide has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Lanzhou Institute of Chemical Physics; Xia, Chungu; Han, Feng; Wang, Lei; Li, Zhen; (27 pag.)CN103073372; (2016); B;,
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