Reference of 14062-80-7,Some common heterocyclic compound, 14062-80-7, name is 4-Chloro-N,N-dimethylbenzamide, molecular formula is C9H10ClNO, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
N’-cyanobenzimidamide (16.8 g, 115 mmol),Compound A-2 (21 g, 115 mmol) and phosphorous oxychloride(12 mL, 128 mmol) was added to 500 mL of acetonitrile, followed by stirring and refluxing for 1 hour.After cooling to room temperature, the resulting solid was filtered,Washed with water and ethanol, and then dried to obtain CompoundA (27.6 g, yield 80%).
The synthetic route of 14062-80-7 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; LG Chem, Ltd.; Kang Min-yeong; Park Tae-yun; Cho Seong-mi; Moon Jeong-uk; Jeong Min-u; Lee Jeong-ha; (29 pag.)KR2019/6353; (2019); A;,
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