Related Products of 120157-96-2, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 120157-96-2, name is Methyl 4-(((tert-butoxycarbonyl)amino)methyl)benzoate, This compound has unique chemical properties. The synthetic route is as follows.
To a cold suspension of LiAlH4 (60 mg, 1.5 mmol) in ether (5 mL) at -78 C. was added dropwise a solution of methyl 4-(N-t-Boc-aminomethyl)benzoate (0.8 g, 3 mmol) in ether (5 mL) and the contents were allowed to warm-up to ambient temp. After 3 h, further amount of LiAlH4 (100 mg) was added and the reaction was continued at room temp for further 10 min. Excess LiAlH4 was destroyed with EtOAc followed by saturated ammonium chloride (1.0 mL), The solid precipitated was filtered and washed with ether. The filtrate was evaporated to give 4-(N-t-Boc-aminomethyl)benzyl alcohol (250 mg, 35%).
The chemical industry reduces the impact on the environment during synthesis Methyl 4-(((tert-butoxycarbonyl)amino)methyl)benzoate. I believe this compound will play a more active role in future production and life.
Reference:
Patent; Eli Lilly and Company; Wayne State University; University of Hawaii; US6680311; (2004); B1;,
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