Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 164332-88-1, name is tert-Butyl (2-(2-bromoethoxy)ethyl)carbamate, A new synthetic method of this compound is introduced below., Quality Control of tert-Butyl (2-(2-bromoethoxy)ethyl)carbamate
General procedure: A mixture of the alkyl halide, nitrogen-containing compound and excess base (NaH for compounds 80 and 81, Cs2CO3 for other compounds) in DMF was stirredat 60 C for 30 min. The reaction was quenched with water and extracted with EA. The organic layer was washed with water and brine, concentrated and purified by column chromatography.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Article; Ngo, Van T.H.; Hoang, Van-Hai; Tran, Phuong-Thao; Ann, Jihyae; Cui, Minghua; Park, Gyungseo; Choi, Sun; Lee, Jiyoun; Kim, Hee; Ha, Hee-Jin; Choi, Kwanghyun; Kim, Young-Ho; Lee, Jeewoo; Bioorganic and Medicinal Chemistry; vol. 26; 5; (2018); p. 1035 – 1049;,
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics