Related Products of 37394-93-7,Some common heterocyclic compound, 37394-93-7, name is 2-Chloro-N-(o-tolyl)acetamide, molecular formula is C9H10ClNO, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
General procedure: A mixture of 2 (265mg, 1.0mmol), different 2-chloro-N-arylacetamide 4a-4q (1.0 mmol) and Et3N (1mL) in methanol (50 mL) was stirred at room temperature for 2 h. After thecompletion of the reaction, the solvent was removed under reduced pressure andthe residue was purified by silica gel column chromatography (EtOAc/petroleumether) to give the title compounds 5a-5q, respectively.
The synthetic route of 37394-93-7 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Wang, Guangcheng; Li, Xin; Wang, Jing; Xie, Zhenzhen; Li, Luyao; Chen, Ming; Chen, Shan; Peng, Yaping; Bioorganic and Medicinal Chemistry Letters; vol. 27; 5; (2017); p. 1115 – 1118;,
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