6292-59-7, name is 4-(tert-Butyl)benzenesulfonamide, belongs to amides-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. Product Details of 6292-59-7
A solution of compound 13 (2.0 g, 4.36 mmol) and commercially available4-tert-butylbenzenesulfoamide (1.0 g, 4.79 mmol) in toluene (30 mL) was treated withK2CO3 (723 mg, 5.23 mmol) and tetra-n-butylammonium bromide (142 mg,0.44 mmol). The reaction mixture was warmed at 100 C for 18 h and cooled downto ambient temperature. The resulting mixture was filtered through a pad of Celite,and the filtrate was diluted with EtOAc (100 mL); washed with aqueous 1N HCl,water, and brine; dried over anhydrous MgSO4; and concentrated under reducedpressure to provide the crude product. Flash chromatography (SiO2, 3percent MeOH?CH2Cl2) to provide 14 as a green foam (1.75 g, 63percent)
The synthetic route of 6292-59-7 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Lee, Chung Ryul; Lee, Sang Yeul; Nam, Tae-Gyu; Synthetic Communications; vol. 44; 17; (2014); p. 2488 – 2493;,
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