Share a compound : 617-36-7

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 617-36-7, name is Ethyl 2-amino-2-oxoacetate, This compound has unique chemical properties. The synthetic route is as follows., Formula: C4H7NO3

In a flame dried round-bottomed flask equipped with a magnetic stir bar and under inert atmosphere (N2), a solution of commercially available oxalamic acid ethyl ester (43.429 g, 370.86 mmol) and Lawesson’s reagent (150.00 g, 370.86 mmol) in toluene (550.0 mL) was stirred at 80 0C for 2 h. The resulting mixture was cooled to rt and CH2CI2 (300 mL) was added. The mixture was filtered and the solvents were removed under reduced pressure. Purification of the residue by FC (CH2CI2) gave the title compound as an orange solid.

According to the analysis of related databases, 617-36-7, the application of this compound in the production field has become more and more popular.

Reference:
Patent; ACTELION PHARMACEUTICALS LTD; WO2009/77990; (2009); A1;,
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics