Adding a certain compound to certain chemical reactions, such as: 7150-72-3, name is tert-Butyl vinylcarbamate, belongs to amides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 7150-72-3, Recommanded Product: 7150-72-3
4-Fluorophenyl benzaldehyde-tosylhydrazone sodium salt (786 mg, 2.5 mmol), N-vinyl-carbamic acid tert-butyl ester (1.432 g, 10 mmol) and benzyltriethylammonium chloride (57 mg, 0.25 mmol) were covered with dioxane (11 ml) under argon. Rh2(OAc)4 (11 mg, 0.025 mmol) was added and the suspension stirred at room temperature for 15 minutes. The slurry became thick and difficult to stir so a further 4 ml of dioxane was added. The mixture was stirred at 75 C. for 2 hours, then shaken between tBuOMe and water. The organic phase was washed with water and NaCl (satd), dried over MgSO4 and evaporated to yield a brown viscous oil (1.353 g), which was chromatographed on silica to yield 2-(4-fluoro-phenyl)-cyclopropyl-carbamic acid tert-butyl ester 369 mg (59%, m.p. 117-118 C.) cis and 125 mg (20% m.p. 102-105 C.) trans. 1H-NMR (CDCl3, signals for the cis isomer) 0.93 (1H, m), 1.32 (9H, s), 2.20 (1H, m), 2.89 (1H, m), 4.23 (1H, m), 6.98 (2H, t), 7.18 (2H, t).
At the same time, in my other blogs, there are other synthetic methods of this type of compound, tert-Butyl vinylcarbamate, and friends who are interested can also refer to it.
Reference:
Patent; SYNGENTA PARTICIPATIONS AG; O’Sullivan, Anthony Cornelius; Loiseleur, Olivier; Stierli, Daniel; Luksch, Torsten; Pitterna, Thomas; US2014/378461; (2014); A1;,
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics