In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 114790-39-5, name is Benzyl (2,2-dimethoxyethyl)carbamate belongs to amides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below. name: Benzyl (2,2-dimethoxyethyl)carbamate
BenzvK ( 6-chloro-2-( 3-chlorobenzoyl)-2, 3, 4,9-tetrahvdro-lH-pyridoi 3, 4-b lindol- l-yl)methyl) carbamate trifluoroacetic acid: To a mixture of benzyl (2,2-dimethoxyethyl)- carbamate (1.71 g, 7.15 mmol) in 2-butanol (30 mL) was added 2-(5-chloro-lH-indol-3-yl)ethan- l-amine (l.53g, 7.86 mmol), TFA (0.74 g) and LEO (1 mL) The mixture was stirred at 100 C for 16 hrs. Then the reaction was cooled to room temperature. The precipitates were collected via filtration to afford benzyl((6-chloro-2-(3-chlorobenzoyl)-2,3,4,9-tetrahydro-lH-pyrido[3,4- b]indol-l-yl)methyl)carbamate trifluoroacetic acid (3.5g, yield: 98.9%) as a white solid. LCMS: [M+H]+= 370.1.
The synthetic route of 114790-39-5 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; RECREO PHARMACEUTICALS LLC; ZHANG, Jing; WANG, Xiang; PODOLL, Jessica, D.; (207 pag.)WO2020/37155; (2020); A1;,
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