Related Products of 216961-61-4,Some common heterocyclic compound, 216961-61-4, name is tert-Butyl (10-aminodecyl)carbamate, molecular formula is C15H32N2O2, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
General procedure 2. Starting compound III: S-Methyl N-cyano-N-(2-methoxy-5-pyridylisothiourea. Starting compound IV: 10-t-Butoxycarbonylaminodecylamine. Purification: Flash chromatography (Eluent 1% NH3(aq) and 0-6% MeOH in CH2Cl2) and crystallization from ether. 13C NMR (CDCl3) delta: 161.2, 158.6, 155.5, 143.3, 137.0, 127.9, 117.3, 110.3, 77.2, 53.2, 41.3, 29.4, 28.9, 28.8, 28.8, 28.6, 28.6, 28.2, 26.2, 26.1
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route tert-Butyl (10-aminodecyl)carbamate, its application will become more common.
Reference:
Patent; Leo Pharmaceutical Products, Ltd. A/S; US6346520; (2002); B1;,
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