Related Products of 713-41-7, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 713-41-7, name is 2-Amino-4-(trifluoromethyl)benzamide belongs to amides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
-(4-Chlorophenyl)-7-trifluoromethyl-3H-quinazolin To a stirred suspension of 2-amino-4-(trifluoromethyl)benzamide (33.6 g, 0.16 mol) in water (750 mL) was added dropwise 4-chlorobenzaldehyde. Iron trichloride hexahydrate (133 g) was then added in portions. The reaction mixture was then heated at reflux for 24 h. After allowing the suspension to cool to room tempera- ture, the precipitate was isolated by vacuum filtration washing with water (3 x 500 mL) and dried under vacuum (10 mbar, 50C). Yield = 50 g, 94%; HPLC-mass spectrometry (LC-MS): 3.7 min, 325 (M+).
The synthetic route of 2-Amino-4-(trifluoromethyl)benzamide has been constantly updated, and we look forward to future research findings.
Reference:
Patent; BASF SE; GROss, Steffen; POHLMAN, Matthias; NARINE, Arun; ROSENBAUM, Claudia; DESHMUKH, Prashant; DICKHAUT, Joachim; BANDUR, Nina Gertrud; KOeRBER, Karsten; KAISER, Florian; VON DEYN, Wolfgang; LANGEWALD, Juergen; CULBERTSON, Deborah L.; EBUENGA, Cecille; WO2011/36074; (2011); A1;,
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics