Simple exploration of 85006-25-3

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 85006-25-3, its application will become more common.

Some common heterocyclic compound, 85006-25-3, name is tert-Butyl (tert-butoxycarbonyl)oxycarbamate, molecular formula is C10H19NO5, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. 85006-25-3

Scheme 1: Reagent and conditions; (a) tert-butyl(tert-butoxycarbonyl)oxycarbamate, iN NaOH, TBAB, DCM; (b) TFA, DCM; (c) 3,3-difluoro-2,2-dimethylbutanoic acid, EDCI, DIEA, DMF, rt, 12h(d) NaH, Mel, THF.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 85006-25-3, its application will become more common.

Reference:
Patent; NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING; ZHANG, Zhiyuan; WANG, Xiaodong; LEI, Xiaoguang; SU, Yaning; HE, Sudan; RUAN, Hanying; SUN, Liming; (103 pag.)WO2016/101885; (2016); A1;,
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics