640-61-9, The chemical industry reduces the impact on the environment during synthesis 640-61-9, name is N,4-Dimethylbenzenesulfonamide, I believe this compound will play a more active role in future production and life.
General procedure: To a mixture of the corresponding sulfonamide (5 mmol), DMAP (0.5 mmol%)and Et3N (1.5 mL, 10 mmol) in CH2Cl2 (10 mL) was added slowly the acyl chloride made above in CH2Cl2 (10 mL) at 0C. The reaction mixture was stirred at room temperature for 2 h. Then the reaction mixture was washed with 5% HCl, brine and H2O. The organic layer was dried over Na2SO4, filtered and evaporated under reduced pressure to give crude product, which was purified by column chromatography on silica gel to afford N-tosylcarboxylic amide.
The chemical industry reduces the impact on the environment during synthesis N,4-Dimethylbenzenesulfonamide. I believe this compound will play a more active role in future production and life.
Reference:
Article; Wang, Chen; Huang, Lingyun; Wang, Fengze; Zou, Gang; Tetrahedron Letters; vol. 59; 23; (2018); p. 2299 – 2301;,
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics