107017-73-2, Name is tert-Butyl (1-(hydroxymethyl)cyclopropyl)carbamate, 107017-73-2, belongs to amides-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows.
Step 2: tert-Butyl[1-(bromomethyl)cyclopropyl]carbamateA solution of 92.5 g of carbon tetrabromide in 150 ml of ether is added at ambient temperature to a solution of 34.5 g of the compound of the above Step 1 and 73.5 g of triphenylphosphine in 750 ml of ether. After stirring for 20 hours, the reaction mixture is filtered and concentrated. Chromatography on silica gel (dichloromethane/cyclohexane: 50/50) allows 15 g of the expected product to be obtained.
Statistics shows that tert-Butyl (1-(hydroxymethyl)cyclopropyl)carbamate is playing an increasingly important role. we look forward to future research findings about 107017-73-2.
Reference:
Patent; LES LABORATOIRES SERVIER; US2010/317698; (2010); A1;,
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics