Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 1882-71-9, name is 2-Amino-5-methoxybenzamide, A new synthetic method of this compound is introduced below., 1882-71-9
General procedure: To a cold (0?5 ¡ãC) stirred suspension of aminobenzamides 15a?f and 20a,b (0.016 mol) in pyridine (13 mL), 0.016 mol of the appropriate phenoxyacetyl chloride 16a?e was added over 30 min. After addition was complete, the solution was stirred for24 h and then poured onto crushed ice. The precipitate was removed by filtration, washed with water, and crystallized from the indicated solvent.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Article; Raffa, Demetrio; Maggio, Benedetta; Plescia, Fabiana; Cascioferro, Stella; Raimondi, Maria Valeria; Cancemi, Gabriella; D’Anneo, Antonella; Lauricella, Marianna; Cusimano, Maria Grazia; Bai, Ruoli; Hamel, Ernest; Daidone, Giuseppe; Bioorganic and Medicinal Chemistry; vol. 23; 19; (2015); p. 6305 – 6316;,
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics