14433-76-2, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 14433-76-2, name is N,N-Dimethylcapramide belongs to amides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
the reaction formula of this embodiment is as follows:In a 25 ml reaction flask, add compound 1a (0.3mmol, 0.1561g), compound 2j (3mmol, 0.5980g), water 1.5 muL), toluene (1.5mL) to dissolve the above materials, and stir the reaction at 80 C. The reaction time is 3h After the reaction was completed, the solvent was removed by spin-drying, and the residue was subjected to flash column chromatography (PE: EA = 30: 1) to obtain pure 3aj (0.0850 g) with a yield of 85%.
The synthetic route of N,N-Dimethylcapramide has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Xuzhou Medical University; Wu Nan; Xu Zhou; Mi Jiajia; Li Chuang; Yuan Changyong; Zheng Yan; (15 pag.)CN110668937; (2020); A;,
Amide – Wikipedia,
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