These common heterocyclic compound, 112-84-5, name is Erucamide, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. 112-84-5
To a solution of LAH (2.30 g, 29.6 mmol) in dry THF (100 mL) was added a solution ofcis-docosenoamide (6) (10.0 g, 29.7 mmol) in dry THF (100 mL) and refluxed. After 12 hthe reaction mixture was cooled and Na2SO4¡¤10H2O was added slowly until the reactionceased. The solution was filtered and concentrated in vacuo to affordcis-docos-13-enylamine (9) (9.55 g, 29.6 mmol, quant.) as a pale yellow oil.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 112-84-5.
Reference:
Article; Reimann, Marcel; Sandjo, Louis P.; Antelo, Luis; Thines, Eckhard; Siepe, Isabella; Opatz, Till; Beilstein Journal of Organic Chemistry; vol. 13; (2017); p. 1430 – 1438;,
Amide – Wikipedia,
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