1882-71-9, Adding some certain compound to certain chemical reactions, such as: 1882-71-9, name is 2-Amino-5-methoxybenzamide, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 1882-71-9.
General procedure: In a sealed tube equipped with a magnetic bar was charged with 2-amino benzamide derivatives (1, 3.67 mmol), cyclic 1,3-diones (2, 3.67 mmol) and TsOH.H2O (1.83mmol) in m-Xylene (5 mL). The reaction mixture was stirred at 150 ¡ãC for 8 h. After completion of the reaction, the reaction mass was cooled to room temperature, diluted with EtOAc, gave a water wash and the organic layer was dried over anhydrous Na2SO4 and concentrated in vacuo. The crude product was purified by flash column chromatography (eluent: ethyl acetate/ n-hexane = 10?90) on silica gel to afford the desired product (4a-k).
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 1882-71-9.
Reference:
Article; Bingi, Chiranjeevi; Kola, Kaushik Yadav; Kale, Ashok; Nanubolu, Jagadeesh Babu; Atmakur, Krishnaiah; Tetrahedron Letters; vol. 58; 11; (2017); p. 1071 – 1074;,
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics