1882-71-9, name is 2-Amino-5-methoxybenzamide, belongs to amides-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. 1882-71-9
General procedure: A solution of anthranilamide (30 mmol) in 1N HCl (120 mL) was stirred at 0 C for 20 min. Then, sodium nitrite (60 mmol) dissolved in deionized water (100 mL) was added dropwise to the above solution for 40 min. After another 2 h of stirringat 0 C, 30% NaOH solution was added slowly to adjustp H value to 8.0. The reaction mixture was allowed to stir vigorously for 15 min. The precipitated product was filtered, washed with deionized water (200 mL), and dried to afford compounds 10 in yields of 40-92%.
Statistics shows that 1882-71-9 is playing an increasingly important role. we look forward to future research findings about 2-Amino-5-methoxybenzamide.
Reference:
Article; Chen, Xiulei; Zhou, Zhen; Li, Zhong; Xu, Xiaoyong; Phosphorus, Sulfur and Silicon and the Related Elements; (2019);,
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics