The chemical industry reduces the impact on the environment during synthesis 14433-76-2, name is N,N-Dimethylcapramide, I believe this compound will play a more active role in future production and life. 14433-76-2
Lambda/,Lambda/-Dimethylhexanamide (1.5g, 10.6mmol) was slowly added to an initially stirred mixture of phosphorus trichloride (2.8ml, 32.2mmol) and phosphorous acid (1.15g, 14.0mmol). The mixture was heated at 7O0C for 2h. After cooling the excess phosphorous trichloride was decanted off and the residue hydrolyzed by the careful addition of plenty of water. This mixture was left to stir for at least 2h, filtered, and the filtrate evaporated to dryness under reduced pressure. The precipitate was taken up in 20ml of water and heated at 1000C for 1h, followed by filtration of the hot solution. The water was evaporated and the desired product was isolated as a colorless solid (1.64g, 54%). 1H NMR (300MHz, D2O): delta = 0.83 (t, J =6.26Hz, 3H), 1.27 (tt, J = 3.50, 7.24Hz, 4H), 1.50 (qd, J = 7.04, 6.98, 8.70Hz, 2H), 1.98 -2.04 (m, 2H), 3.03 (s, 6H)ppm. 13C NMR (75MHz, D2O): delta = 13.22, 21.58, 23.00, 28.93,31.54, 42.07, 69,18ppm. 31P NMR (121MHz, D2O): delta = 4.66ppm. HRMS: m/z calcd. for CaH22NO6P2: 290.0917, found: 290.0904.
The chemical industry reduces the impact on the environment during synthesis 14433-76-2. I believe this compound will play a more active role in future production and life.
Reference:
Patent; HUMBOLDT-UNIVERSITAeT ZU BERLIN; RHEINISCH-WESTFAeLISCHE TECHNISCHE HOCHSCHULE AACHEN (RWTH); ARENZ, Christoph; ROTH, Anke Gundula; UHLIG, Stefan; DRESCHER, Daniela; WO2011/23624; (2011); A1;,
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