782-45-6, These common heterocyclic compound, 782-45-6, name is 4-Amino-N-phenylbenzamide, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
The pale yellow solid was dissolved in 20 ml of dry methylene chloride solution, c was added, a solution of triethylamine (0.07 ml) in dry dichloromethane was added dropwise and the mixture was stirred overnight at room temperature. TLC, filtration and drying were followed by treatment with 10 ml of acetic acid Ethyl acetate was heated to reflux, filtered and dried to give 0.030 g of a yellow solid with a yield of 12.5%.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 782-45-6.
Reference:
Patent; Chinese Academy Of Medical Sciences Pharmaceutical Institute; Xiao Zhiyan; Ye Fei; Tang Yanbo; Tian Jinying; Guo Zongru; Chen Zheng; Zhang Xiaolin; He Yibo; Ma Yiming; Chen Ling; Han Jing; (27 pag.)CN102382076; (2016); B;,
Amide – Wikipedia,
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