354-38-1, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 354-38-1, name is 2,2,2-Trifluoroacetamide, This compound has unique chemical properties. The synthetic route is as follows.
Prepared from Intermediate 5 by a method analogous to that reported by Bolm et ah, Organic Letters, 2004, 6(8), 1305-1307, using trifluoroacetamide and (diacetoxy- iodo)benzene in the presence of dirhodium tetraacetate. 5H (500 MHz, CDCI3) 8.79 (d, J 1.4 Hz, IH), 8.22-8.19 (m, IH), 8.18 (dd, J8.4, 2.0 Hz, IH), 3.56 (s, 3H).
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Reference:
Patent; UCB BIOPHARMA SPRL; CHOVATIA, Prafulkumar Tulshibhai; HUTCHINGS, Martin Clive; KROEPLIEN, Boris; REUBERSON, James Thomas; (102 pag.)WO2016/198401; (2016); A1;,
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics